Tessa Bousfield posted an articleA novel hair screening tool to measure metal levels in the body with a single hair see more
Source: CIM Magazine
Author: Kylie Williams
Hair to replace needles in lead monitoring
A toxicology laboratory near Victoria, British Columbia, has developed a novel hair screening tool to measure metal levels in the body with a single hair. A six-month pilot study involving 100 volunteers at Teck Resources’ zinc and lead smelting and refining complex in Trail, which concluded last month, determined that hair analysis is a sensitive and effective tool to screen for elevated blood lead levels – as well as being quicker and less painful.
“Our goal is to reduce the need for needles,” said Jennie Christensen, CEO and founder of TrichAnalytics. Christensen, a toxicologist, led the study. “We can use hair lead levels as a proxy for what is happening in the blood. We can use any growing hair, as long as the root is intact.”
With sample collection as easy as using tweezers to extract three to five hairs and place them in an envelope, the non-invasive method was welcomed by those smelter workers who are anxious about blood tests using needles.
“As part of Teck’s values and policy, we work to identify and manage occupational health exposures for the protection of longer-term health,” said Corrine Balcaen, Teck’s director of occupational health and hygiene. “We’ve been pleased to support this pilot project, which has the potential to reduce or replace blood sampling for occupational exposure and make it easier and more comfortable for our employees.”
The method could have community applications too, such as blood lead level monitoring of children and families close to industrial sites. Teck partners with the City of Trail and B.C.’s interior health authority on the Trail Area Health and Environment Committee (THEC) to monitor lead levels in children in the surrounding community, which currently collects samples via regular voluntary blood tests.
Trail has historically had high blood lead levels. In 1989, children aged six to 36 months in Trail were registering an average of 13.5 micrograms per decilitre. That is now down to four micrograms per decilitre in 2017, the lowest result to date, according to a THEC release from February. Currently, the Canadian standard for intervention is if blood lead levels are 10 micrograms per decilitre or higher, though the Centers for Disease Control and Prevention in the United States recommends testing for those with five micrograms per decilitre.
At the TrichAnalytics laboratory, once Christensen and her team have received the hair samples, they use Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) to analyze a three-millimetre section of the sample near the root, just below the skin, to eliminate contamination from the environment.
“We designed a statistical algorithm to help us find the sweet spot where blood and hair lead levels match,” said Christensen. “We’re the only lab that is doing it commercially.”
Monitoring industrial lead exposure is critical because at lower concentrations, it can impact the nervous system, resulting in weakened limbs, anemia and increased blood pressure. At high concentration, lead exposure will severely damage the brain and kidneys. In the past, said Christensen, hair samples have been used mainly for nutritional testing, but not for occupational health monitoring as it was viewed as inaccurate and unreliable because of contamination.
The pilot used lessons learned about contamination from the death of seaman John Hartnell during the ill-fated Franklin Expedition in 1845. For a previous study, Christensen was given access to a 170-year-old fingernail belonging to Hartnell. Using x-ray fluorescence, Christensen and her co-authors mapped the distribution of certain elements on the outer surface and underside of the nail, honing a technique to account for contamination in growing tissue and questioning the role of lead in his death.
“The lesson we took from the Franklin study to the occupational health realm was how contamination affects results and how to get around it,” said Christensen, who published her study of the role of lead poisoning during the Franklin Expedition using fingernail analysis in the Journal of Archeological Science in December 2017. “We’re using the protected piece of the hair – protected by the scalp and follicle – so environmental contamination is less of an issue, and coloured, treated, or damaged hair can also be used.”
Christensen’s pilot study was run in parallel with Teck’s regular on-site blood monitoring program. More than 70 per cent of the participants said they would be content with a hair test compared to only nine per cent who preferred a blood test. In the future, the non-invasive hair test could be used to monitor blood lead levels by proxy so, when a certain hair lead level is reached, it triggers a blood test.
TrichAnalytics received funding, in-kind support and access to Trail workers from Teck for the pilot study, and a contribution from the National Research Council of Canada’s Industrial Research Assistance Program. The response to the trial was positive and discussions are underway to expand the program at Trail and beyond, said Christensen.
“We’re looking for forward-thinking companies that are looking to change the way they monitor,” said Christensen, who hopes that with the ease and speed of collecting a single hair sample, the method may evolve into a preventive tool for mines, smelters, refineries, battery manufacturing and recycling plants, and welding facilities, and for the communities surrounding them.
“Instead of a [semi-annual] or annual blood test, we can test hair more regular, perhaps monthly, and see the trend creeping up over time,” said Christensen. “We can do something about it sooner.”
Tessa Bousfield posted an articleThe winners were announced at an awards ceremony on April 4 at The Leonardo Da Vinci Centre see more
Including two VIATEC Members!
April 5, 2017 (News Release) VICTORIA — Douglas magazine is proud to announce the winners of their eighth annual 10 to Watch Awards for 2017. These awards highlight the very best of Vancouver Island’s new businesses.
The winners were announced at an awards ceremony on April 4 at The Leonardo Da Vinci Centre in Victoria, B.C. and were selected by an independent panel of judges that included local business owners and representatives of the University of Victoria Peter B. Gustavson School of Business and Royal Roads University School of Business.
The 2017 10 to Watch winners are:
- TrichAnalytics (VIATEC Member!)
- Roll.Focus. Productions
- Cultured Kombucha
- FreshWorks Studio (VIATEC Member!)
- Studio Robazzo
- Angela Cote Consulting Inc.
- SOHO Victoria
- Miiko Skin Co
- Rep Lab Communications
- Victoria Soda Works
On April 5, you can read more about the 2017 winners here.
“We celebrate each of these innovative 10 to Watch winners for their entrepreneurial spirit and courage to leave the comfort zone,” says Lise Gyorkos, co-owner of Page One Publishing, which produces Douglas magazine. “A 10 to Watch Award is a strong vote of confidence from the experts, and these are businesses who demonstrate sound business models, scalability, talent and great market potential.”
Now in their eighth year, the 10 to Watch Awards recognize Vancouver Island’s best new companies, which have been in business for three years or less. Previous winners include: LlamaZoo, DeeBees Organics, Flytographer, Indochino, Rumble Energy Drink, Elate Cosmetics and Stocksy United.
Douglas is Vancouver Island’s business magazine, published by award-winning Page One Publishing. Page One also publishes YAM magazine, Victoria’s lifestyle magazine.
The 10 to Watch Awards are made possible by the generous sponsorship of Title Sponsor Peninsula Co-op and supporting sponsors.
Douglas Editor-in-Chief, Kerry Slavens and select winners will be available for interviews, upon request.
For further information and interviews, contact:
Kerry Slavens, Editor-in-Chief, Douglas Magazine
ABOUT THE WINNERS:
The only commercial laboratory in Canada to use laser ablation for biological tissues to answer questions regarding health, nutrition and metal exposure.
A video production company that combines a journalistic approach with simple digital marketing strategies, striking the balance between budget and value for its small-business clients.
The maker of kombucha — a probiotic beverage made of fermented tea — which uses organic ingredients and sells it primarily on tap and by bulk-fill, leaving a low environmental footprint.
A tech firm that uses a collaborative team approach to develop elegant and sophisticated mobile apps for private- and public-sector companies, on both iOS and Android platforms.
A multi-faceted design firm that takes on everything from interior design to graphic design to websites to industrial design to retail displays and even stage sets.
A franchise consultant and business-growth specialist who helps business owners convert to the franchise model, and assists established franchisors take their business to the next level.
An annual one-day conference and networking event for small companies and home-based businesses that includes speakers, workshops, round-table discussions and one-on-one expert advisor sessions.
A natural skincare line that focuses on using high-quality local ingredients, delivering its products with education and keeping its environmental footprint low.
A public relations and marketing company that enhances its clients’ reputations in the good times but whose grounding in crisis management can also help when issues arise.
Maker of handcrafted, small-batch soda pop, available in 16 different flavours sweetened with cane sugar, as well as a line of sugar-free selzers.